Supergirl is the new girl in school, and she just also happens to be the most powerful teenager in the galaxy! After losing her home planet of Krypton and everyone she knows, Supergirl has made a new home on Earth, but she's isn't so sure that Super Hero High School is the right place for her. Wonder Woman, other new friends, and a kindly librarian make her feel welcome, but breached inter-dimensional portals, invading alien armies, and bad dreams...

Barbara Gordon is Batgirl and she is ready to train some teenagers in the galaxy.

Wonder Woman, Harley Quinn, Katana, Bumblebee, Supergirl, and Batgirl rush to finish their comic about themselves for June Moone's art class, but when Harley Quinn spills Ms. Moone's magic paint on their pages, their art comes to life-and these super dopplegängers are super-villains! As the dastardly doodles cause chaos in Metropolis, Ms. Moone discovers this havoc is a result of her pilfered potions and her out-of-control anger transforms her into...