Y, the last man

As the last remaining Y-chromosome carriers on the planet, Yorrick and his pet monkey are the key to the fate of humanity; teamed up with a government agent and the world's premier bioengineer, they travel across the country, dodging the man-hating Daughters of the Amazon, who are determined to kill the last man on Earth.

Yorick Brown, the last man on Earth, finds himself fighting for survival when he is placed in the care of retired government agent 711 in the backcountry of Colorado while his companions, cloning specialist Dr. Allison Mann and government agent 355, go in search of antibiotics for Brown's monkey Ampersand, the planet's only other living male.

It's 2002, and a plague of unknown origin has killed all of the male mammals on Earth-all except an amateur escape artist named Yorick Brown and his surly helper monkey, Ampersand. As the last remaining & -chromosome carriers on the planet, Yorick and his pet hold the fate of humanity in their hands.

Five years after the sudden death of all male animals except callow but not stupid 21-year-old Yorick Brown and his pet monkey, Ampersand, Yorick is finally reunited with Beth, the fianc©♭e with whom he was talking when the dying started. And with the other Beth, who has borne his daughter in the interim (this is news to him). The reunifications don't really work out, and Yorick decides he loves another, as it happens, too late. Then the story...