Drs. Ephraim Goodweather and Nora Martinez race to create a biological weapon to destroy the creatures, Abraham Setrakian relentlessly searches for an ancient book that holds the key to defeating the sinister Master. Aware that he is now hunted by his handful of unlikely allies, the Master creates even more unstoppable bloodthirsty monsters.

Darren McGavin portrays crusading reporter Carl Kolchak. In the first episode, Kolchak tries to solve a series of Las Vegas murders. In the second, he's after a killer hiding in Seattle's underground city.

The war between the bloodthirsty strigoi and the remaining human survivors of New York intensifies. Although Dr. Ephraim Goodweather's bioweapon initially helped stave off the vampiric creatures, they have evolved into a bigger threat to humanity than ever. Now, distraught over his kidnapped son, Eph teams with Dutch to search for signs of weakness in the strigoi.

The monster family embarks on a vacation on a luxury monster cruise ship so Drac can take a summer vacation from providing everyone else's vacation at the hotel. It's smooth sailing for Drac's Pack as the monsters indulge in all of the shipboard fun the cruise has to offer. But the dream vacation turns into a nightmare when Mavis realizes Drac has fallen for the mysterious captain of the ship, Ericka, who hides a dangerous secret that could destroy...