Only Captain Underpants can stop the three evil space aliens who have invaded Jerome Horwitz Elementary School and turned everyone into lunchroom zombie nerds.

Third-grader Vera, a budding artist who loves every minute of her after-school comic-book camp, searches for a way to get her mother's permission to attend the camp's final field trip to Comic-Con.

This is the journey of Laika, the abandoned puppy destined to become Earth's first space traveler. With the blending of fact and fiction, this story intertwines three compelling lives. Along with Laika, there is Korolev, a driven engineer at the top of the Soviet space program and Yelena, the lab technician responsible for Laika's health and life.

Convinced he should have died in the accident that killed his parents and sister, sixteen-year-old Drew lives in a hospital, hiding from employees and his past, until Rusty, set on fire for being gay, turns his life around. Includes excerpts from the superhero comic Drew creates.

Buzz creates a comic book that features Buzz Boy and Fly Guy as the superheroes.

When George and Harold hypnotize their principal into thinking that he is the superhero Captain Underpants, he leads them to the lair of the nefarious Dr. Diaper, where they must defeat his evil robot henchmen.